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KMID : 0360220130540101534
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Journal of the Korean Ophthalmological Society
2013 Volume.54 No. 10 p.1534 ~ p.1539
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Incidence of New Choroidal Neovascularization in Fellow Eyes of Patients Treated for Age-Related Macular Degeneration
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Lee Jung-Jin
Lew Young-Ju
Cho Sung-Won
Kim Jong-Woo
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Abstract
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Purpose: To investigate the development of new choroidal neovascularization in fellow eyes of patients treated for unilateral exudative age-related macular degeneration (AMD).
Methods: Three hundred fourteen patients who were first diagnosed with unilateral exudative AMD and treated with intravitreal bevacizumab or ranibizumab were studied retrospectively.
Results: New exudative AMD developed in 7.0% of fellow eyes after 1 year, 10.8% after 2 years and 13.7% after more than 2 years. According to the subtype of exudative AMD, there were no significant differences between classic CNV, occult or minimally classic CNV, and PCV in the incidence of new exudative AMD. After 2 years, a higher conversion rate was found in the bevacizumab-treated group than the ranibizumab-treated group.
Conclusions: The cumulative incidence of involvement in fellow eyes with exudative AMD was 13.7% over 2 years.
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KEYWORD
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Bevacizumab, Exudative age-related macular degeneration, Incidence, Ranibizumab
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